Friday, February 26, 2010

Why Symptoms of Schizophrenia Emerge in Young Adulthood

ScienceDaily (Feb. 26, 2010) — In reports of two new studies, researchers led by Johns Hopkins say they have identified the mechanisms rooted in two anatomical brain abnormalities that may explain the onset of schizophrenia and the reason symptoms don't develop until young adulthood. Both types of anatomical glitches are influenced by a gene known as DISC1, whose mutant form was first identified in a Scottish family with a strong history of schizophrenia and related mental disorders. The findings could lead to new ways to treat, prevent or modify the disorder or its symptoms.

full article can be found at this link

Wednesday, February 10, 2010

Have Your Say On New Psychiatric Manual

By Alix Spiegel

Finally, after years of work, the American Psychiatric Association has put out the list of mental illnesses it intends to include in its new Diagnostic and Statistical Manual of Mental Disorders.
Have your say on a new psychiatric guide.

A new guidebook to the psychiatrist's couch is coming.

The DSM, as it's called for short, is incredibly influential. Doctors use it to diagnose patients, of course, but insurance companies also consult it in their decisions about reimbursements. Courts, schools, governments and researchers also turn to the manual for guidance on behavior that deviates from normal.

The manual and the secretive process for its drafting have attracted their share of controversy over the years. And the APA has been careful to say that this is a "proposed draft" of the new DSM, the fifth edition. For the first time, the group is inviting "public input."

Anyone--including you--can log on and tell the nice people working on DSM their thoughts about, say, the new proposed Temper Dysregulation Disorder. You have 10 weeks to speak up.

The people at the APA say they are doing this because they want to be transparent and take advantage of the Internet, but doing this could create some problems.

There are quite a few hot-button changes like the elimination of Asperger's that are sure to inflame passions. What will the APA do if Asperger's groups rally the troops and organize a write-in campaign? Will Asperger's be put back?

The APA has made a big deal of the DSM being the product of an intense scientific process. So if the group changes the contents based on interest group politics, they open themselves to fresh criticism that the DSM is less scientific than claimed.

Tuesday, February 2, 2010

Fish oils 'beat mental illness'

Taking a daily fish oil capsule can stave off mental illness in those at highest risk, trial findings suggest.

A three-month course of the supplement appeared to be as effective as drugs, cutting the rate of psychotic illness like schizophrenia by a quarter.

The researchers believe it is the omega-3 in fish oil - already hailed for promoting healthy hearts - that has beneficial effects in the brain.

A "natural" remedy would be welcomed, Archives of General Psychiatry says.

"The finding that treatment with a natural substance may prevent, or at least delay, the onset of psychotic disorder gives hope that there may be alternatives to antipsychotic drugs," the study authors said.

“ If young people can be treated successfully with fish oils, this is hugely preferable to treating them with antipsychotics ”
Alison Cobb Mind

Antipsychotic drugs are potent and can have serious side effects, which puts some people off taking them.

Fish oil supplements, on the other hand, are generally well tolerated and easy to take, say the scientists.

The international team from Austria, Australia and Switzerland tested the treatment in 81 people deemed to be at particularly high risk of developing psychosis.

Natural choice

Their high risk was down to a strong family history of schizophrenia, or similar disorders, or them already showing mild symptoms of these conditions themselves.

For the test, half of the individuals took fish oil supplements (1.2 grams of omega-3 fatty acids) for 12 weeks, while the other half took only a dummy pill. Neither group knew which treatment they were receiving.

Dr Paul Amminger and his team followed the groups for a year to see how many, if any, went on to develop illness.

Two in the fish oil group developed a psychotic disorder compared to 11 in the placebo group.

Based on the results, the investigators estimate that one high-risk adult could be protected from developing psychosis for every four treated over a year.

They believe the omega-3 fatty acids found in the supplements may alter brain signalling in the brain with beneficial effects.

Alison Cobb, of the mental health charity Mind, said: "If young people can be treated successfully with fish oils, this is hugely preferable to treating them with antipsychotics, which come with a range of problems from weight gain to sexual dysfunction, whereas omega-3s are actually beneficial to their general state of health.

"These are promising results and more research is needed to show if omega-3s could be an alternative to antipsychotics in the long term."

Story from BBC NEWS:
http://news.bbc.co.uk/go/pr/fr/-/2/hi/health/8490937.stm

Published: 2010/02/02 00:02:02 GMT

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