Traditionally, depression is suspected when symptoms that suggest impaired psychosocial functioning are present for more than two weeks. Symptoms of depression include an overwhelming feeling of sadness, difficulty to experience pleasure, sleep problems, and difficulties with engaging in everyday life.
Emerging research addresses the neural bases of depression as well as how treatment can induce changes in the brain. Modern brain imaging techniques such as functional magnetic resonance imaging (fMRI) are often used to view brain modulations.
This line of research expands the commonly accepted premise that depression is associated with dysfunction of specific brain regions involved in cognitive control and emotional response.
Source: European College of Neuropsychopharmacology
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